What is a common clinical use of trimethoprim-sulfamethoxazole in small animals, and what is a notable adverse effect?

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Multiple Choice

What is a common clinical use of trimethoprim-sulfamethoxazole in small animals, and what is a notable adverse effect?

Explanation:
Trimethoprim-sulfamethoxazole is a broad-spectrum antibacterial that targets a wide range of bacteria and also has activity against some protozoa. In small animals, it’s commonly used for urinary tract infections and skin/soft tissue infections, and it can be effective against certain protozoal infections such as Toxoplasma gondii. A notable adverse effect, especially in dogs, is hypersensitivity reactions and keratoconjunctivitis sicca (KCS, dry eye) with sulfonamide use. Other possible issues include GI upset and nephrotoxicity in susceptible animals.

Trimethoprim-sulfamethoxazole is a broad-spectrum antibacterial that targets a wide range of bacteria and also has activity against some protozoa. In small animals, it’s commonly used for urinary tract infections and skin/soft tissue infections, and it can be effective against certain protozoal infections such as Toxoplasma gondii. A notable adverse effect, especially in dogs, is hypersensitivity reactions and keratoconjunctivitis sicca (KCS, dry eye) with sulfonamide use. Other possible issues include GI upset and nephrotoxicity in susceptible animals.

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