Which alpha-2 agonist is FDA-approved in horses and used as a premed prior to general anesthesia?

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Study for the Veterinary Pharmacology Drugs Test. Prepare with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

Multiple Choice

Which alpha-2 agonist is FDA-approved in horses and used as a premed prior to general anesthesia?

Explanation:
Alpha-2 adrenergic agonists provide sedation and analgesia by dampening sympathetic outflow through CNS receptors, making them ideal premeds before anesthesia in many species. In horses, Romifidine is the alpha-2 agonist that is FDA-approved for equine use specifically as a premed. It’s formulated for horses and reliably produces calming effects with some analgesia, helping smooth the path to induction of anesthesia. The other options are anticholinergic drugs that reduce secretions or counter vagal effects but do not act as alpha-2 agonists, so they don’t fulfill the role of the alpha-2 premed in this context.

Alpha-2 adrenergic agonists provide sedation and analgesia by dampening sympathetic outflow through CNS receptors, making them ideal premeds before anesthesia in many species. In horses, Romifidine is the alpha-2 agonist that is FDA-approved for equine use specifically as a premed. It’s formulated for horses and reliably produces calming effects with some analgesia, helping smooth the path to induction of anesthesia. The other options are anticholinergic drugs that reduce secretions or counter vagal effects but do not act as alpha-2 agonists, so they don’t fulfill the role of the alpha-2 premed in this context.

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